RM CLARITHROMYCIN 500 MG TAB

Antibacterial

Product Details

What is this medicine used for?

·         For the treatment of the following infections caused by susceptible microorganisms:

  • Upper respiratory tract infections including streptococcal pharyngitis and  tonsillitis
  • Acute otitis media and acute maxillary sinusitis
  • Lower respiratory tract infections including atypical pneumonia, bronchitis
  • Skin and skin structure infections including impetigo, folliculitis, cellulitis, abscesses (abscesses usually require surgical drainage)
  • Disseminated or localized mycobacterial infections due to Mycobacterium intracellulare or Mycobacterium avium. Localized infections due to Mycobacterium kansasii, Mycobacterium chelonae and Mycobacterium fortuitum (usually in combination with other antimicrobial agents)
  • Helicobacter pylori infections (in combination with other drugs)

Odontogenic infections

How much and how often should you use this medicine?

Clarithromycin tablets and suspension may be given with or without food. Clarithromycin suspension may be given with milk.

 

INDICATIONS

  

RECOMMENDED ORAL ADULT DOSE

  

RECOMMENDED ORAL

 

PEDIATRIC DOSE
 

 Non-Mycobacterial Infections

 

 

  

Usual adult dose: 250 to 500 mg every 12 hours for 7 to 14 days, depending on the type and severity of infection.

  

Usual pediatric dose: 15 mg/kg body weight/day to be given in two divided doses every 12 hours for 5 to 10 days depending on the type and severity of infection.

 
 

Age Group

  

Recommended Dose every

 

12 hours
 

6 months to 1 year

  

2.5 mL

 

(1/2 teaspoonful)
 

2 to 6 years

  

5 mL

 

(1 teaspoonful)
 

7 to 12 years

  

7.5 to 10 mL

 

(1 ½ to

 

2 teaspoonsful)
 

 
 

 Disseminated or Localized Mycobacterial Infections

 

 

  

500 mg every 12 hours.

 

Treatment should be continued for as long as clinical improvement is observed.

 

Concomitant treatment with other anti- mycobacterial drugs may be beneficial.

  

15 to 30 mg/kg body weight/day to be given in two divided doses every           12 hours (up to a maximum of 500 mg every 12 hours).

 

Treatment should be continued for as long as clinical improvement is observed.

 

Concomitant treatment with other anti-mycobacterial drugs may be beneficial.

 

 

Prophylaxis of Mycobacterium avium complex (MAC) Infections in HIV+/AIDS patients

  

500 mg every 12 hours.

 

Treatment should be continued while CD4 count is less than 100/mm3.

  

15 mg/kg body weight/day to be given in two divided doses (up to a maximum of       500 mg every 12 hours).

 

Treatment should be continued while CD4 count is less than 100/mm3.
 

Treatment of MAC Infections in HIV+/AIDS patients

 

 

  

500 mg every 12 hours.

 

Treatment should be continued for as long as   clinical improvement is observed.

 

Clarithromycin should be used in combination with other antimycobacterial drugs with activity against MAC, such as ethambutol, rifabutin and rifampicin.

  

15 to 30 mg/kg body weight/day to be given in two divided doses (up to a maximum of 500 mg every 12 hours).

 

Treatment should be continued for as long as clinical improvement is observed.

 

Clarithromycin should be used in combination with other antimycobacterial drugs with activity against MAC, such as ethambutol, rifabutin and rifampicin.
 

 Helicobacter pylori infections

 

 

  

Triple therapy regimens:

Clarithromycin 500 mg plus amoxicillin 1000 mg plus omeprazole 20 mg, all twice daily for 7 to 10 days, OR

 

Clarithromycin 500 mg plus amoxicillin 1000 mg plus pantoprazole 40 mg, all twice daily for one week

 

 

 

Dual therapy regimen:

 

Clarithromycin 500 mg three times daily plus omeprazole 40 mg once daily for

 

14 days, followed by omeprazole 20 mg or

 

40 mg once daily for an additional 14 days.

  

 

 

--
 

Odontogenic infections

  

250 mg every 12 hours

 

for 5 days

  

--
 

Or, as prescribed by a physician.

 

Contraindications

  • Hypersensitivity to Clarithromycin or any ingredient in the product
  • Cisapride, Pimozide, Astamizole, Tefernadine, Ergotamine, Dihydroergotamine: risk of arrhythmia (abnormal heart rhythm)
  • Warfarin: increased risk of bleeding
  • Carbamazepine: drowsiness, dizziness
  • Colchicine:  may cause nausea, vomiting, abdominal pain
  • Ciclosporin: increased risk of kidney toxicity
  • Digoxin: increase risk of digoxin toxicity
  • Atorvastatin, Simvastatin: muscle pain and weakness
  • Triazolam: increased risk of drowsiness and confusion

 

Availability

  • Clarithromycin 500 mg Tablet - Boxes of 50’s (in blister pack by 10’s)

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RM CHLORPHENAMINE 5 MG TAB 100 BOX

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RM ASCORBIC ACID 500 MG TAB

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RM VERAPAMIL 240 MG TAB

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RM CLOPIDOGREL 75 MG TAB

RM CLOPIDOGREL 75 MG TAB

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RM LANSOPRAZOLE 30 MG CAP

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RM SILDENAFIL 100 MG TAB

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RM PARAMAX 9+1 BS PH (PACK)

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RM LORATADINE 10 MG TAB

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RM SODIUM ASCORBATE CAP

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RM NAPROXEN SODIUM 500 MG TAB

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RM ATORVASTATIN 20 MG TAB

Php 16.50
RM TELMISARTAN + HTCZ 40 MG

RM TELMISARTAN + HTCZ 40 MG

Php 16.50
RM CELECOXIB 200 MG CAP

RM CELECOXIB 200 MG CAP

Php 23.50
RM AMOXICILLIN 250 MG CAP

RM AMOXICILLIN 250 MG CAP

Php 5.50
RM CEFUROXIME 150 MG VIAL

RM CEFUROXIME 150 MG VIAL

Php 242.86
RM HYDROCORTISONE 15 G CRM 1BOX

RM HYDROCORTISONE 15 G CRM 1BOX

Php 215.00
RM OLMESARTAN 20 MG TAB

RM OLMESARTAN 20 MG TAB

Php 32.00
RM RELAXING OIL

RM RELAXING OIL

Php 56.00
RM BETAMETHASONE 250 MCG/2 MG TABLET

RM BETAMETHASONE 250 MCG/2 MG TABLET

Php 15.00
RM FRUSEMA 20 MG TAB 100 BOX

RM FRUSEMA 20 MG TAB 100 BOX

Php 3.44
RM LAGUNDI SYRUP 60 ML

RM LAGUNDI SYRUP 60 ML

Php 90.00
RM GLICLAZIDE 30 MG

RM GLICLAZIDE 30 MG

Php 7.00
RM CEFACLOR 50 MG DROPS 20 ML

RM CEFACLOR 50 MG DROPS 20 ML

Php 264.00
RM ALFUZOSIN HCI 10 MG TAB

RM ALFUZOSIN HCI 10 MG TAB

Php 46.00
RM CEFUROXIME AXETIL 250 MG TAB

RM CEFUROXIME AXETIL 250 MG TAB

Php 31.00
RM TRI-V

RM TRI-V

Php 157.50
RM AMOXICILLIN 125 MG SUSPENSION 60 ML

RM AMOXICILLIN 125 MG SUSPENSION 60 ML

Php 77.00
RM MEFENAMIC ACID 500 MG TAB

RM MEFENAMIC ACID 500 MG TAB

Php 4.75
RM LOSARTAN 100 MG TAB

RM LOSARTAN 100 MG TAB

Php 16.79
RM LOPERAMIDE CAP 9+1

RM LOPERAMIDE CAP 9+1

Php 5.50
RM HEXETIDINE 60 ML

RM HEXETIDINE 60 ML

Php 89.00
RM CETIRIZINE 5 MG SYRUP 60 ML

RM CETIRIZINE 5 MG SYRUP 60 ML

Php 200.00
RM CO-AMOXICLAV 1 G TAB

RM CO-AMOXICLAV 1 G TAB

Php 58.75
RM PARAMAX TAB 9+1

RM PARAMAX TAB 9+1

Php 45.00
RM STOP COUGH (LAGUNDI) 300 MG/5 ML SYR 60 ML

RM STOP COUGH (LAGUNDI) 300 MG/5 ML SYR 60 ML

Php 95.00
RM ENALAPRIL 20 MG

RM ENALAPRIL 20 MG

Php 16.00
RM ATENOLOL 100 MG TAB

RM ATENOLOL 100 MG TAB

Php 12.00
RM INSULYF 30/70 100 IU/ML VIAL

RM INSULYF 30/70 100 IU/ML VIAL

Php 700.00
RM BOMAX + D (ALENDRONIC ACID + VITAMIN D3) 70 MG / 2800 IU TAB

RM BOMAX + D (ALENDRONIC ACID + VITAMIN D3) 70 MG / 2800 IU TAB

Php 300.00
RM LOSARTAN + HYDROCHLOROTHIAZIDE (LOSARITE) 50 MG TAB

RM LOSARTAN + HYDROCHLOROTHIAZIDE (LOSARITE) 50 MG TAB

Php 13.25
RM APPETITE STIMULANT TAB

RM APPETITE STIMULANT TAB

Php 15.00
RM CLONIDINE HCL 150 MCG TAB

RM CLONIDINE HCL 150 MCG TAB

Php 26.00
RM STOP COUGH (LAGUNDI) 300 MG/5 ML SYR 120 ML

RM STOP COUGH (LAGUNDI) 300 MG/5 ML SYR 120 ML

Php 122.50
RM CLOTRIMAZOLE 3 G

RM CLOTRIMAZOLE 3 G

Php 90.00
RM ISONIAZID + PYRIDOXINE HYDROCHLORIDE 200 MG/ 12 MG PER 5 ML SYRUP

RM ISONIAZID + PYRIDOXINE HYDROCHLORIDE 200 MG/ 12 MG PER 5 ML SYRUP

Php 50.00
RM GLICLAZIDE 80 MG TAB

RM GLICLAZIDE 80 MG TAB

Php 6.75
RM COTTON ROLL 10 G

RM COTTON ROLL 10 G

Php 5.50
RM GLUCLAZIDE SR 60 MG

RM GLUCLAZIDE SR 60 MG

Php 15.00
RM COTTON BALLS 100S

RM COTTON BALLS 100S

Php 48.00
RM PARAMAX (IBUPROFEN+PARACETAMOL) 32 5MG/200 MG TAB

RM PARAMAX (IBUPROFEN+PARACETAMOL) 32 5MG/200 MG TAB

Php 5.00
RM CETIRIZINE TAB 18+2

RM CETIRIZINE TAB 18+2

Php 342.00
RM OMEPRAZOLE TAB 9+1

RM OMEPRAZOLE TAB 9+1

Php 21.00
RM ISOPROPYL 70% ALCOHOL 60 ML

RM ISOPROPYL 70% ALCOHOL 60 ML

Php 22.50
RM BETAMETHASONE DIPROPIONATE 500 MCG/ G CREAM

RM BETAMETHASONE DIPROPIONATE 500 MCG/ G CREAM

Php 245.00
RM AMLODIPINE BESILATE 5 MG TAB

RM AMLODIPINE BESILATE 5 MG TAB

Php 6.47
RM NEUTRACID TAB 9+1 (ALUMINUM HYDROXIDE + MAGNESIUM HYDROXIDE)

RM NEUTRACID TAB 9+1 (ALUMINUM HYDROXIDE + MAGNESIUM HYDROXIDE)

Php 3.00