RM CEFALEXIN 125MG SUSPENSION 60 ML

Infections

Product Details

What is this medicine used for?

For the treatment of the following infections by susceptible microorganism: Skin and skin structure infections. Bone and joint infections. Genitourinary tract infections, including acute prostatic. Respiratory tract infection including acute and chronic bronchitis and infected bronchiectasis. Ear, nose and throat infection including otitis media, mastoiditis, sinusitis, follicular sinusitis, and pharyngitis. Dental infections. 

 

How much and how often should you use this medicine?

Use in adult: 250mg every 6 hours ( Maximum dose: 4g/day) Usual Pediatric Dose: 25 to 50 mg/kg body weight/day to be given in equally divided doses every 6  hours. 

 

Contraindication:

Known hypersensitivity to cephalosporins, penicllins, or any component of the product. 

 

Warnings and Precautions:

Careful inquiry should be made prior to cefalexin therapy to determine whether before the patient has had previous hypersensitivity reactions to cefalexin, cephalosporins, penicillins, or other drugs. Use with caution in patient with penicillin-sensitive patients since cross-sensitive among beta lactam antibiotics has been clearly documented and may occur in up to 10% of patients with a history of allergy to penicillin. In case of an allergic reaction to cefalexin, the drug should be discontinued. Serious acute hypersensitivity reactions may require immediate treatment with epinephrine and other emergency measures, including oxygen, intravenous fluids, corticosteroids, pressor amines, and airway management, as clinically indicated. Clostridium difficile-associated diarrhea (CDAD) and colitis have been reported with the use of nearly all antibacterial agents, including amoxicillin, and may range in severity from mild to life threatening. It is important to consider this diagnosis in patients who present with diarrhea following administration of antibacterial agents. Cephalosporins, including cefalexin, have been associated with the development of seizures, particularly in patients with renal impairment, in whom dosage of drug was not reduced. If seizures due to cefalexin develop, the drug should be discontinued and the treatment with an anticonvulsant be given as clinically indicated. Cephalosporins may be associated with a fall in prothrombin activity. Patients who are at risk are those with renal or hepatic impairment or poor nutritional state, as well as patients receiving protracted course of antimicrobial therapy, and patients stabilized on anticoagulant therapy. prothrombin time should be monitored in patients at risk and exogenous Vitamin K administered as indicated. A false-positive comb's test has been reported during treatment with other cephalosporins antibiotics; therefore, it should be recognized that a positive coombs test may be due to the drug, e.g., coombs testing of new burns whose mother has receive cephalosporins before parturitions or in hematologic studies or in transfusion cross-matching procedures where anti- globulin test are performed. Use with caution in patients with renal impairment. Careful clinical and laboratories would be made since safe dosage may be lower than that usually recommended. Indicated surgical procedures. As any potent drug, periodic assessment of organ system function, including renal, hepatic , hematopoietic, is recommended during prolonged therapy. Prescribing cefalexin in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to patient and increase the risk of antibiotic resistance. As with other antibacterial drugs, long term or repeated use may result in overgrowth in non-susceptible organisms, including fungi. 

 

Undesirable Effects:

GI: abdominal cramp/pain, anorexia, CDAD, and colitis, diarrhea, dyspepsia, gastritis, gastroenteritis, glossitis/stomatitis, nausea, vomiting. Dermatologic: Anaphylaxis, angioedema, eosinophilia, erythema multiforme, fever, genital and anal pruritis, intertrigo, pruritus, rash, serum sickness-like reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria. Hematologic: Decreased hemoglobin and/or hemotocrit, hemolytic anemia, reversible leukopenia; neutropenia, decreased platelets; positive direct and in direct ant globulin test results; thrombocytopenia. Renal and Genitourinary: Transient increase in blood urea nitrogen(BUN) and serum creatinine concentrations; dysuria, reversible interstitial nephritis, nephrotoxicity, leukorrhea, pruritus vulvae, vaginal discharges, vulvo-vaginitis. Hepatic; Transient increase in serum alanine aminotransferase(ALT), aspartate aminotransferase(AST), and alkaline phosphatase concentrations; increased serum bilirubin; transient hepatitis and cholestatic jaundice. Nervous System; agitation, confusion, diplopia, dizziness, fatigue, headache, hallucinations, insomnia, malaise, paresthesia, somnolence, tremor, toxic paranoid reactions. Vertigo, tinnitus, hearing loss and behavioral changes in young children have been reported with cefalexin use. Other AE; Arthralgia, myalgia, arthritis, joint disorder back pain, nuchal swelling, cardiac arrhythmia, vasodilation, dyspnea, superinfection, elevated cholesterol. 

 

Interaction w/ other medicaments:

No potentially hazardous interactions has been reported. However, it may share the interaction of other cephalosporins as with the following: Alcohol: Disulfiram-like reactions have occurred when alcohol was ingested with 48-72 hours after administration of beta lactam antibiotics that contain n-methylthiotetrazole side chain. The reactions appear to result from accumulation of acetaldehyde and do not occur if alcohol is ingested prior to the first dose of antibiotic ingestion of alcohol during 24 to 72 hours after administration of some cephalosporins should be avoided. Estrogen or Progestin: Some cephalosporins reabsorption and reduced efficacy of oral contraceptives. Metformin: when single 500 mg doses of cefalexin and metformin were given to 12 healthy subjects, plasma metformin Cmax and AUC increased by an average 34% and 24%, respectively, the metformins are multiple renal clearance decreased by an average of 14%. Information on the interaction of cefalexin and metformin after multiple doses of administration is unavailable. Careful patient monitoring and metformin dose adjustment is recommended during concomitant therapy. Nephrotoxic drugs: Concurrent use of nephrotoxic agents such as aminoglycosides, colistin, polymixin B, or vancomycin may increase the risk of nephrotoxicity with some cephalosporins and probably be avoided, if possible. Diuretics: concurrent treatment with high doses of cephalosporins and potent diuretics (e.g., furosemide) may adversely affect renal function. 

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Php 46.00
RM SALBUTAMOL 2 MG SYR 60 ML

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Php 2.75
RM ALLOPURINOL 100 MG TAB

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Php 6.00
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Php 25.00
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Php 21.00
RM FELODIPINE 5 MG TAB

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Php 12.75
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RM HAND SANITIZER

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Php 7.50
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Php 135.00
RM COLCHICINE 500 MCG

RM COLCHICINE 500 MCG

Php 4.35
RM BISACODYL 5 MG SUPPOSITORY (CONLAX-5)

RM BISACODYL 5 MG SUPPOSITORY (CONLAX-5)

Php 39.00
RM REMOSTON TAB 5+1

RM REMOSTON TAB 5+1

Php 35.00
RM TRAMADOL + PARACETAMOL

RM TRAMADOL + PARACETAMOL

Php 40.00
RM CEFACLOR 50 MG DROPS 20 ML

RM CEFACLOR 50 MG DROPS 20 ML

Php 264.00
RM VERAPAMIL 240 MG TAB

RM VERAPAMIL 240 MG TAB

Php 42.50
RM CARBOCISTEINE 500 MG

RM CARBOCISTEINE 500 MG

Php 6.50
RM IRON+FOLIC TAB

RM IRON+FOLIC TAB

Php 4.00
RM RABEPRAZOLE 20 MG TABLET

RM RABEPRAZOLE 20 MG TABLET

Php 70.00
RM COTTON ROLL 100 G

RM COTTON ROLL 100 G

Php 56.25
RM CETIRIZINE TAB 18+2

RM CETIRIZINE TAB 18+2

Php 342.00
RM RELAXING OIL

RM RELAXING OIL

Php 56.00
RM ATENOLOL 100 MG TAB

RM ATENOLOL 100 MG TAB

Php 12.00
RM MOMETASONE 1 MG/ G (0.1% W/W) 5 G CREAM

RM MOMETASONE 1 MG/ G (0.1% W/W) 5 G CREAM

Php 290.00
RM METFORMIN 850 MG TAB

RM METFORMIN 850 MG TAB

Php 7.50
RM COTTON BALLS 100S

RM COTTON BALLS 100S

Php 48.00
RM SILDENAFIL 50 MG TAB

RM SILDENAFIL 50 MG TAB

Php 150.00
RM PARAMAX (IBUPROFEN+PARACETAMOL)  32 5MG/200 MG TAB

RM PARAMAX (IBUPROFEN+PARACETAMOL) 32 5MG/200 MG TAB

Php 5.00
KIN WHITENING 75 ML

KIN WHITENING 75 ML

Php 262.56
RM PARAMAX 9+1 BS PH (PACK)

RM PARAMAX 9+1 BS PH (PACK)

Php 45.00
RM LEVOFLOXACIN 500 MG TAB

RM LEVOFLOXACIN 500 MG TAB

Php 54.00
RM DENGUETROL 15% 100 ML

RM DENGUETROL 15% 100 ML

Php 120.00
RM HEXETIDINE 120 ML

RM HEXETIDINE 120 ML

Php 148.00
RM MELOXICAM 7.5 MG TAB

RM MELOXICAM 7.5 MG TAB

Php 29.00
RM ISONIAZID + PYRIDOXINE HYDROCHLORIDE 200 MG/ 12 MG PER 5 ML SYRUP

RM ISONIAZID + PYRIDOXINE HYDROCHLORIDE 200 MG/ 12 MG PER 5 ML SYRUP

Php 50.00
RM SIMVASTATIN 20 MG TAB

RM SIMVASTATIN 20 MG TAB

Php 16.00
RM BISOPROLOL 5 MG TAB

RM BISOPROLOL 5 MG TAB

Php 15.00
RM POVIDONE IODINE 10% SOL 60 ML

RM POVIDONE IODINE 10% SOL 60 ML

Php 90.00
KIN GINGIVAL COMPLEX MOUTHWASH 250 ML

KIN GINGIVAL COMPLEX MOUTHWASH 250 ML

Php 623.15
RM ZELEXIN 250 MG CAP

RM ZELEXIN 250 MG CAP

Php 14.50
RM HYDROCORTISONE 15 G CRM 1BOX

RM HYDROCORTISONE 15 G CRM 1BOX

Php 215.00
RM OMEPRAZOLE 9+1 BS PH (PACK)

RM OMEPRAZOLE 9+1 BS PH (PACK)

Php 189.00
RM ATORVASTATIN 10 MG TAB

RM ATORVASTATIN 10 MG TAB

Php 13.00
RM METRONIDAZOLE 10 MG/ G GEL

RM METRONIDAZOLE 10 MG/ G GEL

Php 328.00
RM NEUTRACID 9+1 BS PH (PACK)

RM NEUTRACID 9+1 BS PH (PACK)

Php 3.00
RM ATORVASTATIN 20 MG TAB

RM ATORVASTATIN 20 MG TAB

Php 16.50
RM SODIUM ASCORBATE CAP

RM SODIUM ASCORBATE CAP

Php 4.50
RM BISOPROLOL 10 MG TAB

RM BISOPROLOL 10 MG TAB

Php 24.50
RM CINNARIZINE 25 MG TAB VERZIRON

RM CINNARIZINE 25 MG TAB VERZIRON

Php 36.00
RM PIOGLITAZONE 150 MG TAB

RM PIOGLITAZONE 150 MG TAB

Php 16.00
RM AMLODIPINE BESILATE 5 MG TAB

RM AMLODIPINE BESILATE 5 MG TAB

Php 6.47
RM STOP COUGH (LAGUNDI) 300 MG/5 ML SYR 120 ML

RM STOP COUGH (LAGUNDI) 300 MG/5 ML SYR 120 ML

Php 122.50
RM VALSARTAN 80 MG

RM VALSARTAN 80 MG

Php 17.86
RM LINEZOLID 2 MG SOL 1 BAG

RM LINEZOLID 2 MG SOL 1 BAG

Php 4,144.00
RM LAGUNDI SYRUP 60 ML

RM LAGUNDI SYRUP 60 ML

Php 90.00
RM ETHYL ALCOHOL 70% 60 ML

RM ETHYL ALCOHOL 70% 60 ML

Php 22.00
RM CEFACLOR 500 MG CAP

RM CEFACLOR 500 MG CAP

Php 79.50
RM METFORMIN SR 500 MG TAB

RM METFORMIN SR 500 MG TAB

Php 6.25
RM DICLOFENAC SODIUM 50 MG TAB

RM DICLOFENAC SODIUM 50 MG TAB

Php 16.00
RM AMLODIPINE BESILATE 10 MG TAB

RM AMLODIPINE BESILATE 10 MG TAB

Php 9.00
RM CEFUROXIME AXETIL 250 MG TAB

RM CEFUROXIME AXETIL 250 MG TAB

Php 31.00
RM AMBROXOL 30 MG SYRUP 60 ML

RM AMBROXOL 30 MG SYRUP 60 ML

Php 80.00